Christian Brueffer

Christian Brueffer

Biomedical Data Scientist

SAGA Diagnostics

Lund University

About Me

I am a Biomedical Data Scientist currently working as Senior Bioinformatician at the cancer diagnostics company SAGA Diagnostics. Additionally I conduct research in affiliation with Lund University in Sweden.

My work focuses on the development of diagnostics based on tumor DNA and RNA sequencing to improve treatment and survival of cancer patients. Many of my projects, including my doctoral thesis, have been embedded in the Sweden Cancerome Analysis Network–Breast (SCAN-B) breast cancer study. Additionally I work on improving open source bioinformatics and reproducible research infrastructure by contributing to projects such as conda-forge, Bioconda, and Biopython.

Over the past 20 years I have contributed to a number of open source software projects, most notably the FreeBSD computer operating system. A rough overview can be found on OpenHub and GitHub.

Interests
  • Data Science and Bioinformatics
  • Cancer Biology and Diagnostics
  • Open Source Software
  • Software Engineering
Education
  • PhD in Medical Science and Cancer Genomics

    Lund University, Sweden

  • MSc in Bioinformatics

    Lund University, Sweden

  • BSc in Scientific Programming

    Aachen University of Applied Sciences, Germany

Recent Publications

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(2022). PrecisionFDA Truth Challenge V2: Calling variants from short and long reads in difficult-to-map regions. Cell Genomics, 2022. 2(5): 100129.

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(2022). Molecular and Serologic Diagnostic Technologies for SARS-CoV-2. arXiv, 2022.

Preprint Project DOI

(2022). Clinical associations of ESR2 (estrogen receptor beta; ERβ) expression across thousands of primary breast tumors. Scientific Reports, 2022. 12:4696.

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