RNA Sequencing

Clinical associations of ESR2 (estrogen receptor beta; ERβ) expression across thousands of primary breast tumors
Estrogen receptor alpha (ERα, encoded by ESR1) is a well-characterized transcription factor expressed in more than 75% of breast tumors …
Hina Dalal, Malin Dahlgren, Sergii Gladchuk, Christian Brueffer, Sofia K. Gruvberger-Saal, Lao H. Saal
DOI PDF Dataset
Clinical associations of ESR2 (estrogen receptor beta; ERβ) expression across thousands of primary breast tumors
Preexisting Somatic Mutations of Estrogen Receptor Alpha (ESR1) in Early-Stage Primary Breast Cancer
Background
More than three-quarters of primary breast cancers are positive for estrogen receptor alpha (ER; encoded by the gene ESR1), …
Malin Dahlgren, Anthony M. George, Christian Brueffer, Sergii Gladchuk, Yilun Chen, Johan Vallon-Christersson, Cecilia Hegardt, Jari Häkkinen, Lisa Rydén, Martin Malmberg, Christer Larsson, Sofia K. Gruvberger-Saal, Anna Ehinger, Niklas Loman, Åke Borg, Lao H. Saal
DOI PDF Dataset Press Release
Preexisting Somatic Mutations of Estrogen Receptor Alpha (ESR1) in Early-Stage Primary Breast Cancer
PhD Project: RNA Sequencing-based Tools for Breast Cancer Diagnostics
My PhD work in developing RNA sequencing-based diagnostic tools for breast cancer.
PhD Project: RNA Sequencing-based Tools for Breast Cancer Diagnostics
The mutational landscape of the SCAN-B real-world primary breast cancer transcriptome
Breast cancer is a disease of genomic alterations, of which the panorama of somatic mutations and how these relate to subtypes and …
Christian Brueffer, Sergii Gladchuk, Christof Winter, Johan Vallon-Christersson, Cecilia Hegardt, Jari Häkkinen, Anthony M. George, Yilun Chen, Anna Ehinger, Christer Larsson, Niklas Loman, Martin Malmberg, Lisa Rydén, Åke Borg, Lao H. Saal
DOI PDF bioRxiv Preprint Code Dataset Press Release PhD Project
The mutational landscape of the SCAN-B real-world primary breast cancer transcriptome
Features of increased malignancy in eosinophilic clear cell renal cell carcinoma
Clear cell renal cell carcinoma (ccRCC) is the most common form of renal cancer. Due to inactivation of the von Hippel–Lindau tumour …
Helén Nilsson, David Lindgren, Håkan Axelson, Christian Brueffer, Lao H. Saal, Jaana Lundgren, Martin Johansson
DOI PDF
Features of increased malignancy in eosinophilic clear cell renal cell carcinoma
Defining the Mutational Landscape of 3,217 Primary Breast Cancer Transcriptomes through large-scale RNA-seq within the Sweden Cancerome Analysis Network: Breast Project (SCAN-B; NCT03430492)
May 29, 2020 08:00 — 11:00 ASCO Annual Meeting 2020 McCormick Place, Chicago, IL, USA
PhD Project MutationExplorer Project
SCAN-B MutationExplorer
A web-based application for exploring tumor somatic mutations.
SCAN-B MutationExplorer
Defining the Mutational Landscape of the Primary Breast Cancer Transcriptome through large-scale RNA-seq in the SCAN-B Project
Nov 4, 2019 10:45 — 11:05 Swedish Cancer Research Meeting 2019 Folkets Hus, Umeå, Sweden
PhD Project MutationExplorer Project
Towards Better Breast Cancer Diagnostics: Large-scale Profiling of Tumor Transcriptomes
May 23, 2019 09:10 — 09:35 RSG-Sweden Bioinformatics in Diseases Symposium Ekologihuset, Lund, Sweden
PhD Project MutationExplorer Project
RNA-seq-Based Classifiers for Prediction of the Five Conventional Breast Cancer Biomarkers in the Population-Based Multicenter SCAN-B Study
May 7, 2018 16:15 — 16:30 Keystone Symposium on Precision Medicine in Cancer Clarion Hotel Sign, Stockholm, Sweden
PhD Project